Bundesliga:
| Freitag 21 Januar 2022 | ||
| Eintracht Frankfurt | 21:30 | Arminia Bielefeld |
| Samstag 22 Januar 2022 | ||
| TSG 1899 Hoffenheim | 16:30 | Borussia Dortmund |
| Greuther Fürth | 16:30 | Mainz |
| Bayer 04 Leverkusen | 16:30 | Augsburg 1907 |
| SC Freiburg | 16:30 | Stuttgart |
| Borussia Mönchengladbach | 16:30 | Union Berlin |
| VFL Bochum | 19:30 | FC Cologne |
| Sonntag 23 Januar 2022 | ||
| RB Leipzig | 16:30 | Wolfsburg |
| Hertha Berlin | 18:30 | Bayern Munich |
| Freitag 4 Februar 2022 | ||
| Hertha Berlin | 21:30 | VFL Bochum |
| Samstag 5 Februar 2022 | ||
| Stuttgart | 16:30 | Eintracht Frankfurt |
| Mainz | 16:30 | TSG 1899 Hoffenheim |
| Augsburg 1907 | 16:30 | Union Berlin |
| Arminia Bielefeld | 16:30 | Borussia Mönchengladbach |
| FC Cologne | 16:30 | SC Freiburg |
| Bayern Munich | 19:30 | RB Leipzig |
| Sonntag 6 Februar 2022 | ||
| Borussia Dortmund | 16:30 | Bayer 04 Leverkusen |
| Wolfsburg | 18:30 | Greuther Fürth |
| Freitag 11 Februar 2022 | ||
| RB Leipzig | 21:30 | FC Cologne |
Bundesliga Ergebnisse:
| # | Mannschaft | Spiele | S | U | N | T | GT | TD | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Bayern Munich | 19 | 15 | 1 | 3 | 61 | 18 | +43 | 46 |
| 2 | Borussia Dortmund | 19 | 13 | 1 | 5 | 49 | 29 | +20 | 40 |
| 3 | Bayer 04 Leverkusen | 19 | 9 | 5 | 5 | 44 | 31 | +13 | 32 |
| 4 | TSG 1899 Hoffenheim | 19 | 9 | 4 | 6 | 39 | 29 | +10 | 31 |
| 5 | Union Berlin | 19 | 8 | 7 | 4 | 27 | 24 | +3 | 31 |
| 6 | SC Freiburg | 19 | 8 | 6 | 5 | 31 | 23 | +8 | 30 |
| 7 | RB Leipzig | 19 | 8 | 4 | 7 | 36 | 23 | +13 | 28 |
| 8 | Eintracht Frankfurt | 19 | 7 | 7 | 5 | 30 | 28 | +2 | 28 |
| 9 | FC Cologne | 19 | 7 | 7 | 5 | 30 | 32 | -2 | 28 |
| 10 | Mainz | 19 | 8 | 3 | 8 | 27 | 21 | +6 | 27 |
| 11 | VFL Bochum | 19 | 7 | 2 | 10 | 17 | 27 | -10 | 23 |
| 12 | Borussia Mönchengladbach | 19 | 6 | 4 | 9 | 25 | 35 | -10 | 22 |
| 13 | Hertha Berlin | 19 | 6 | 4 | 9 | 21 | 38 | -17 | 22 |
| 14 | Wolfsburg | 19 | 6 | 3 | 10 | 17 | 30 | -13 | 21 |
| 15 | Augsburg 1907 | 19 | 4 | 7 | 8 | 19 | 30 | -11 | 19 |
| 16 | Arminia Bielefeld | 19 | 3 | 9 | 7 | 18 | 26 | -8 | 18 |
| 17 | Stuttgart | 19 | 4 | 6 | 9 | 22 | 33 | -11 | 18 |
| 18 | Greuther Fürth | 19 | 1 | 4 | 14 | 15 | 51 | -36 | 7 |